Gene Set: E2F1_UP.V1_DN

Standard name E2F1_UP.V1_DN
Systematic name M2630
Brief description Genes down-regulated in mouse fibroblasts over-expressing E2F1 [GeneID=1869] gene.
Full description or abstract Identification of E2F1-regulated genes that modulate the transition from quiescence into DNA synthesis, or have roles in apoptosis, signal transduction, membrane biology, and transcription repression.
Collection C6: oncogenic signature gene sets
Source publication Pubmed 11888208   Authors: Ma Y,Croxton R,Moorer RL Jr,Cress WD
Exact source E2F1 vs BetaGal; bottom 200 genes (diff. of means)
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Organism Mus musculus
Contributed by Pablo Tamayo (Broad Institute)
Source platform HUMAN_GENE_SYMBOL
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Compendia expression profiles GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
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