Human Gene Set: GOBP_CANONICAL_WNT_SIGNALING_PATHWAY

For the Mouse gene set with the same name, see GOBP_CANONICAL_WNT_SIGNALING_PATHWAY

Standard name GOBP_CANONICAL_WNT_SIGNALING_PATHWAY
Systematic name M12752
Brief description A type of Wnt signaling pathway in which Wnt binding to its receptor on the surface of a target cell results in the by propagation of the molecular signals via beta-catenin, and end with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. [PMID:11532397, PMID:19619488]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:BP: GO Biological Process
Source publication  
Exact source GO:0060070
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0060070
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
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Version history 2025.1.Hs: Updated to GO Release 2025-03-16.


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