Human Gene Set: GOBP_CANONICAL_WNT_SIGNALING_PATHWAY

For the Mouse gene set with the same name, see GOBP_CANONICAL_WNT_SIGNALING_PATHWAY

Standard name GOBP_CANONICAL_WNT_SIGNALING_PATHWAY
Systematic name M12752
Brief description The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. [GOC:bf, GOC:dph, PMID:11532397, PMID:19619488]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:BP: GO Biological Process
Source publication  
Exact source GO:0060070
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0060070
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
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