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Human Gene Set: GOBP_CANONICAL_WNT_SIGNALING_PATHWAY
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| Standard name | GOBP_CANONICAL_WNT_SIGNALING_PATHWAY_INVOLVED_IN_CARDIAC_MUSCLE_CELL_FATE_COMMITMENT |
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| Systematic name | M40485 |
| Brief description | The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin and contributing to cardiac muscle cell fate commitment. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. [GOC:mtg_heart, PMID:17576928] |
| Full description or abstract | |
| Collection | C5: Ontology GO: Gene Ontology GO:BP: GO Biological Process |
| Source publication | |
| Exact source | GO:0061317 |
| Related gene sets | |
| External links | http://amigo.geneontology.org/amigo/term/GO:0061317 |
| Filtered by similarity ? | |
| Source species | Homo sapiens |
| Contributed by | Gene Ontology (Gene Ontology Consortium) |
| Source platform or identifier namespace |
Human_NCBI_Gene_ID |
| Dataset references | |
| Download gene set | format: grp | gmt | xml | json | TSV metadata |
| Compute overlaps ? |
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| Compendia expression profiles ? |
NG-CHM interactive heatmaps (Please note that clustering takes a few seconds) Legacy heatmaps (PNG) |
| Advanced query | Further investigate these 5 genes |
| Gene families ? | Categorize these 5 genes by gene family |
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| Version history |
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