Human Gene Set: GOBP_HIPPO_SIGNALING

For the Mouse gene set with the same name, see GOBP_HIPPO_SIGNALING

Standard name GOBP_HIPPO_SIGNALING
Systematic name M11445
Brief description The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1. [PMID:17318211, PMID:18328423]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:BP: GO Biological Process
Source publication  
Exact source GO:0035329
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0035329
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
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