Human Gene Set: GOCC_RETROMER_COMPLEX
For the Mouse gene set with the same name, see GOCC_RETROMER_COMPLEX
Standard name
GOCC_RETROMER_COMPLEX
Systematic name
M16994
Brief description
A conserved hetero-pentameric membrane-associated complex involved in retrograde transport from endosomes to the Golgi apparatus. The budding yeast retromer comprises Vps35p, Vps29p, Vps26p, Vps5p, and Vps17p. The mammalian complex shows slight variation in composition compared to yeast, and comprises SNX1 or SNX2, SNX5 or SNX6, VPS26A or VPS26B, VPS29, and VPS35. [GOC:bf, PMID:26220253, PMID:27385586, PMID:9700157]
Full description or abstract
Collection
C5: Ontology GO: Gene Ontology GO:CC: GO Cellular Component
Source publication
Exact source
GO:0030904
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0030904
Filtered by similarity ?
Source species
Homo sapiens
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Human_NCBI_Gene_ID
Dataset references
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Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 12 genes
Gene families ?
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12 genes by gene family
Show members
(show 12 source identifiers mapped to 12 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
112936
112936
VPS26B
VPS26 retromer complex component B [Source:...
27131
27131
SNX5
sorting nexin 5 [Source:HGNC Symbol;Acc:HGN...
29934
29934
SNX12
sorting nexin 12 [Source:HGNC Symbol;Acc:HG...
51699
51699
VPS29
VPS29 retromer complex component [Source:HG...
55667
55667
DENND4C
DENN domain containing 4C [Source:HGNC Symb...
55737
55737
VPS35
VPS35 retromer complex component [Source:HG...
58533
58533
SNX6
sorting nexin 6 [Source:HGNC Symbol;Acc:HGN...
6642
6642
SNX1
sorting nexin 1 [Source:HGNC Symbol;Acc:HGN...
6643
6643
SNX2
sorting nexin 2 [Source:HGNC Symbol;Acc:HGN...
8724
8724
SNX3
sorting nexin 3 [Source:HGNC Symbol;Acc:HGN...
9559
9559
VPS26A
VPS26 retromer complex component A [Source:...
9779
9779
TBC1D5
TBC1 domain family member 5 [Source:HGNC Sy...
Version history
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