Human Gene Set: HP_RENAL_AMYLOIDOSIS


Standard name HP_RENAL_AMYLOIDOSIS
Systematic name M41247
Brief description Renal amyloidosis
Full description or abstract A form of amyloidosis that affects the kidney. On hematoxylin and eosin stain, amyloid is identified as extracellular amorphous material that is lightly eosinophilic. These deposits often stain weakly for periodic acid Schiff (PAS), demonstrate a blue-to-gray hue on the trichrome stain and are typically negative on the Jones methenamine silver (JMS) stain. These tinctorial properties contrast with the histologic appearance of collagen, a major component of basement membranes, mesangial matrix and areas of sclerosis, which demonstrates strong positivity for PAS and JMS (See Figure 1 of PMID:25852856). [https://orcid.org/0000-0002-0736-9199, PMID:25852856]
Collection C5: Ontology
      HPO: Human Phenotype Ontology
Source publication  
Exact source HP:0001917
Related gene sets  
External links https://hpo.jax.org/app/browse/term/HP:0001917
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Source species Homo sapiens
Contributed by Human Phenotype Ontology Group (The Jackson Laboratory (JAX))
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references  
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Version history 2023.1.Hs: Updated to HPO Release 2023-01-27.

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