Gene Set: YAP1_DN

Standard name YAP1_DN
Systematic name M2841
Brief description Genes down-regulated in MCF10A cells (breast cancer) over-expressing YAP1 [GeneID=10413] gene.
Full description or abstract MCF10A cells were infected with retrovirus constructs (vector or YAP) and puromycin was used to select for transduced cells. Cells were split and grown to ~60-75%% confluency at which point they were harvested for RNA. Vector vs. YAP comparison was done in duplicate.
Collection C6: oncogenic signature gene sets
Source publication Pubmed 18413746   Authors: Zhang J,Smolen GA,Haber DA
Exact source YAP1 vs control; bottom 50 genes
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(show 96 gene sets from the same authors)
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Organism Homo sapiens
Contributed by Pablo Tamayo (Broad Institute)
Source platform HUMAN_GENE_SYMBOL
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Compendia expression profiles GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
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