Mouse Gene Set: GOBP_ERK1_AND_ERK2_CASCADE

For the Human gene set with the same name, see GOBP_ERK1_AND_ERK2_CASCADE

Standard name GOBP_ERK1_AND_ERK2_CASCADE
Systematic name MM9544
Brief description An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade may involve 4 different kinases, as it can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell. [GOC:add, GOC:signaling, ISBN:0121245462, ISBN:0896039986, PMID:20811974, PMID:28903453]
Full description or abstract  
Collection M5: Ontology
      GO: Gene Ontology
            GO:BP: GO Biological Process
Source publication  
Exact source GO:0070371
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0070371
Filtered by similarity ? (show 1 similar ontology term(s) from the external resource)
Source species Mus musculus
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Mouse_NCBI_Gene_ID
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
Mouse Transcriptomic BodyMap compendium

Legacy heatmaps (PNG)
Mouse Transcriptomic BodyMap compendium
Advanced query Further investigate these 376 genes
Show members (show 377 source identifiers mapped to 376 genes)
Version history  

See MSigDB license terms here. Please note that certain gene sets have special access terms.