Mouse Gene Set: LEIN_CHOROID_PLEXUS_MARKERS
For the Human gene set with the same name, see LEIN_CHOROID_PLEXUS_MARKERS
Standard name
LEIN_CHOROID_PLEXUS_MARKERS
Systematic name
MM1214
Brief description
Genes enriched in choroid plexus cells in the brain identified through correlation-based searches seeded with the choroid plexus cell-type specific gene expression patterns.
Full description or abstract
Molecular approaches to understanding the functional circuitry of the nervous system promise new insights into the relationship between genes, brain and behaviour. The cellular diversity of the brain necessitates a cellular resolution approach towards understanding the functional genomics of the nervous system. We describe here an anatomically comprehensive digital atlas containing the expression patterns of approximately 20,000 genes in the adult mouse brain. Data were generated using automated high-throughput procedures for in situ hybridization and data acquisition, and are publicly accessible online. Newly developed image-based informatics tools allow global genome-scale structural analysis and cross-correlation, as well as identification of regionally enriched genes. Unbiased fine-resolution analysis has identified highly specific cellular markers as well as extensive evidence of cellular heterogeneity not evident in classical neuroanatomical atlases. This highly standardized atlas provides an open, primary data resource for a wide variety of further studies concerning brain organization and function.
Collection
M2: Curated CGP: Chemical and Genetic Perturbations
Source publication
Pubmed 17151600 Authors: Lein ES,Hawrylycz MJ,Ao N,Ayres M,Bensinger A,Bernard A,Boe AF,Boguski MS,Brockway KS,Byrnes EJ,Chen L,Chen L,Chen TM,Chin MC,Chong J,Crook BE,Czaplinska A,Dang CN,Datta S,Dee NR,Desaki AL,Desta T,Diep E,Dolbeare TA,Donelan MJ,Dong HW,Dougherty JG,Duncan BJ,Ebbert AJ,Eichele G,Estin LK,Faber C,Facer BA,Fields R,Fischer SR,Fliss TP,Frensley C,Gates SN,Glattfelder KJ,Halverson KR,Hart MR,Hohmann JG,Howell MP,Jeung DP,Johnson RA,Karr PT,Kawal R,Kidney JM,Knapik RH,Kuan CL,Lake JH,Laramee AR,Larsen KD,Lau C,Lemon TA,Liang AJ,Liu Y,Luong LT,Michaels J,Morgan JJ,Morgan RJ,Mortrud MT,Mosqueda NF,Ng LL,Ng R,Orta GJ,Overly CC,Pak TH,Parry SE,Pathak SD,Pearson OC,Puchalski RB,Riley ZL,Rockett HR,Rowland SA,Royall JJ,Ruiz MJ,Sarno NR,Schaffnit K,Shapovalova NV,Sivisay T,Slaughterbeck CR,Smith SC,Smith KA,Smith BI,Sodt AJ,Stewart NN,Stumpf KR,Sunkin SM,Sutram M,Tam A,Teemer CD,Thaller C,Thompson CL,Varnam LR,Visel A,Whitlock RM,Wohnoutka PE,Wolkey CK,Wong VY,Wood M,Yaylaoglu MB,Young RC,Youngstrom BL,Yuan XF,Zhang B,Zwingman TA,Jones AR
Exact source
Table 1S: Choroid Plexus-enriched
Related gene sets
(show 9 additional gene sets from the source publication)
(show 9 gene sets from the same authors)
External links
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Jessica Robertson (MSigDB Team)
Source platform or identifier namespace
MOUSE_GENE_SYMBOL
Dataset references
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Advanced query
Further investigate
these 105 genes
Show members
(show 108 source identifiers mapped to 105 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
1110059M19Rik
68800
Prr32
proline rich 32 [Source:MGI...
1500015O10Rik
78896
Ecrg4
ECRG4 augurin precursor [So...
1700027N10Rik
75564
Rsph9
radial spoke head 9 homolog...
4930513F16Rik
74717
Spata17
spermatogenesis associated ...
4932438H23Rik
74387
4932438H23Rik
RIKEN cDNA 4932438H23 gene ...
4933405A16Rik
74442
Sgms2
sphingomyelin synthase 2 [S...
4933431N12Rik
71310
Tbc1d9
TBC1 domain family, member ...
A430107O13Rik
214642
Cped1
cadherin-like and PC-estera...
AI987712
19116
Prlr
prolactin receptor [Source:...
Abca4
11304
Abca4
ATP-binding cassette, sub-f...
Acaa2
52538
Acaa2
acetyl-Coenzyme A acyltrans...
Acacb
100705
Acacb
acetyl-Coenzyme A carboxyla...
Acad8
66948
Acad8
acyl-Coenzyme A dehydrogena...
Ace
11421
Ace
angiotensin I converting en...
Adh1
11522
Adh1
alcohol dehydrogenase 1 (cl...
Als2cr4
381259
Tmem237
transmembrane protein 237 [...
Atp6v0e
11974
Atp6v0e
ATPase, H+ transporting, ly...
B230308G19Rik
242721
Klhdc7a
kelch domain containing 7A ...
BC013481
245945
Rbm47
RNA binding motif protein 4...
BC013491
211535
Odad1
outer dynein arm docking co...
C230095G01Rik
319776
Tmem72
transmembrane protein 72 [S...
C330016K18Rik
232156
Slc4a5
solute carrier family 4, so...
C730036B14Rik
104806
Fancm
Fanconi anemia, complementa...
Cab39l
69008
Cab39l
calcium binding protein 39-...
Calml4
75600
Calml4
calmodulin-like 4 [Source:M...
Ccnd3
12445
Ccnd3
cyclin D3 [Source:MGI Symbo...
Cdh3
12560
Cdh3
cadherin 3 [Source:MGI Symb...
Cfh
12628
Cfh
complement component factor...
Cldn1
12737
Cldn1
claudin 1 [Source:MGI Symbo...
Cldn2
12738
Cldn2
claudin 2 [Source:MGI Symbo...
Col8a1
12837
Col8a1
collagen, type VIII, alpha ...
Col8a2
329941
Col8a2
collagen, type VIII, alpha ...
Col9a3
12841
Col9a3
collagen, type IX, alpha 3 ...
Csrp2
13008
Csrp2
cysteine and glycine-rich p...
Ctsc
13032
Ctsc
cathepsin C [Source:MGI Sym...
D16Ertd642e
212517
Cfap44
cilia and flagella associat...
Dnali1
75563
Dnali1
dynein, axonemal, light int...
Dusp22
105352
Dusp22
dual specificity phosphatas...
E030013G06Rik
233813
Vwa3a
von Willebrand factor A dom...
Efs
13644
Efs
embryonal Fyn-associated su...
Elovl7
74559
Elovl7
ELOVL family member 7, elon...
Ephx1
13849
Ephx1
epoxide hydrolase 1, micros...
F13a1
74145
F13a1
coagulation factor XIII, A1...
F5
14067
F5
coagulation factor V [Sourc...
Fads1
76267
Fads1
fatty acid desaturase 1 [So...
Fhad1
329977
Fhad1
forkhead-associated (FHA) p...
Folr1
14275
Folr1
folate receptor 1 (adult) [...
Fxyd1
56188
Fxyd1
FXYD domain-containing ion ...
Fzd4
14366
Fzd4
frizzled class receptor 4 [...
Gc
14473
Gc
vitamin D binding protein [...
Ggh
14590
Ggh
gamma-glutamyl hydrolase [S...
Gm782
Hemk1
69536
Hemk1
HemK methyltransferase fami...
Itgb5
16419
Itgb5
integrin beta 5 [Source:MGI...
Kcne2
246133
Kcne2
potassium voltage-gated cha...
Kdr
16542
Kdr
kinase insert domain protei...
Kif9
16578
Kif9
kinesin family member 9 [So...
Kl
16591
Kl
klotho [Source:MGI Symbol;A...
LOC332942
332942
Ldc1
leucine decarboxylase 1 [So...
LOC381538
381538
Mroh7
maestro heat-like repeat fa...
Lbp
16803
Lbp
lipopolysaccharide binding ...
Lepr
16847
Lepr
leptin receptor [Source:MGI...
Lgals3bp
19039
Lgals3bp
lectin, galactoside-binding...
Lrp10
65107
Lrp10
low-density lipoprotein rec...
Lum
17022
Lum
lumican [Source:MGI Symbol;...
Mcpt7
100503895
Tpsab1
tryptase alpha/beta 1 [Sour...
Mglap
17313
Mgp
matrix Gla protein [Source:...
Msx1
17701
Msx1
msh homeobox 1 [Source:MGI ...
Mxra8
74761
Mxra8
matrix-remodelling associat...
Myo7a
17921
Myo7a
myosin VIIA [Source:MGI Sym...
Nek11
208583
Nek11
NIMA (never in mitosis gene...
Nid2
18074
Nid2
nidogen 2 [Source:MGI Symbo...
Notch2
18129
Notch2
notch 2 [Source:MGI Symbol;...
Nxn
18230
Nxn
nucleoredoxin [Source:MGI S...
Otx2
18424
Otx2
orthodenticle homeobox 2 [S...
Pbxip1
229534
Pbxip1
pre B cell leukemia transcr...
Pcolce
18542
Pcolce
procollagen C-endopeptidase...
Pcolce2
76477
Pcolce2
procollagen C-endopeptidase...
Perp
64058
Perp
PERP, TP53 apoptosis effect...
Pgcp
54381
Cpq
carboxypeptidase Q [Source:...
Pgpep1
66522
Pgpep1
pyroglutamyl-peptidase I [S...
Pltp
18830
Pltp
phospholipid transfer prote...
Prlr
19116
Prlr
prolactin receptor [Source:...
Rbp1
19659
Rbp1
retinol binding protein 1, ...
Rnaset2
100037283
Rnaset2a
ribonuclease T2A [Source:MG...
Slc24a5
317750
Slc24a5
solute carrier family 24, m...
Slc26a11
268512
Slc26a11
solute carrier family 26, m...
Slc39a12
277468
Slc39a12
solute carrier family 39 (z...
Slco1c1
58807
Slco1c1
solute carrier organic anio...
Sostdc1
66042
Sostdc1
sclerostin domain containin...
Spint2
20733
Spint2
serine protease inhibitor, ...
St6galnac2
20446
St6galnac2
ST6 (alpha-N-acetyl-neurami...
Steap
Steap2
74051
Steap2
six transmembrane epithelia...
Stra6
20897
Stra6
stimulated by retinoic acid...
Sulf1
240725
Sulf1
sulfatase 1 [Source:MGI Sym...
Syne2
319565
Syne2
spectrin repeat containing,...
Tcn2
21452
Tcn2
transcobalamin 2 [Source:MG...
Temt
21743
Inmt
indolethylamine N-methyltra...
Tgfbi
21810
Tgfbi
transforming growth factor,...
Tmprss11a
194597
Tmprss11a
transmembrane protease, ser...
Trpv4
63873
Trpv4
transient receptor potentia...
Ttc21a
74052
Ttc21a
tetratricopeptide repeat do...
Ttr
22139
Ttr
transthyretin [Source:MGI S...
Txnip
56338
Txnip
thioredoxin interacting pro...
Vil2
22350
Ezr
ezrin [Source:MGI Symbol;Ac...
Wfdc2
67701
Wfdc2
WAP four-disulfide core dom...
Xtrp3s1
102680
Slc6a20a
solute carrier family 6 (ne...
Version history
2022.1.Mm: First Introduced.
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