Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | p53_full_useme_maxed_cs.gct |
| Phenotype | MUT |
| GeneSet | s2.symbols.gmt#MAPK_Cascade |
| Enrichment Score (ES) | -0.4923334 |
| Normalized Enrichment Score (NES) | -1.6097703 |
| Nominal p-value | 0.021008404 |
| FDR q-value | 0.49444783 |
| FWER p-Value | 0.862 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MAP2K7 | MAP2K7 StanfordSource, GeneCards | mitogen-activated protein kinase kinase 7 | 465 | 0.304 | 0.0433 | No |
| 2 | MAP2K6 | MAP2K6 StanfordSource, GeneCards | mitogen-activated protein kinase kinase 6 | 1438 | 0.211 | 0.0089 | No |
| 3 | MAP3K3 | MAP3K3 StanfordSource, GeneCards | mitogen-activated protein kinase kinase kinase 3 | 2126 | 0.167 | -0.0100 | No |
| 4 | MAPK3 | MAPK3 StanfordSource, GeneCards | mitogen-activated protein kinase 3 | 2905 | 0.125 | -0.0504 | No |
| 5 | MBP | MBP StanfordSource, GeneCards | myelin basic protein | 3258 | 0.109 | -0.0534 | No |
| 6 | MAP2K4 | MAP2K4 StanfordSource, GeneCards | mitogen-activated protein kinase kinase 4 | 4310 | 0.060 | -0.1399 | No |
| 7 | BRAF | BRAF StanfordSource, GeneCards | v-raf murine sarcoma viral oncogene homolog B1 | 4737 | 0.043 | -0.1696 | No |
| 8 | MAP2K3 | MAP2K3 StanfordSource, GeneCards | mitogen-activated protein kinase kinase 3 | 4998 | 0.031 | -0.1865 | No |
| 9 | MAPK10 | MAPK10 StanfordSource, GeneCards | mitogen-activated protein kinase 10 | 5221 | 0.022 | -0.2021 | No |
| 10 | JUN | JUN StanfordSource, GeneCards | v-jun sarcoma virus 17 oncogene homolog (avian) | 5283 | 0.019 | -0.2025 | No |
| 11 | MAP2 | MAP2 StanfordSource, GeneCards | microtubule-associated protein 2 | 6815 | -0.052 | -0.3390 | No |
| 12 | MAPK1 | MAPK1 StanfordSource, GeneCards | mitogen-activated protein kinase 1 | 8361 | -0.139 | -0.4515 | Yes |
| 13 | MAPK14 | MAPK14 StanfordSource, GeneCards | mitogen-activated protein kinase 14 | 8605 | -0.156 | -0.4298 | Yes |
| 14 | RAF1 | RAF1 StanfordSource, GeneCards | v-raf-1 murine leukemia viral oncogene homolog 1 | 8728 | -0.164 | -0.3937 | Yes |
| 15 | MAP3K1 | MAP3K1 StanfordSource, GeneCards | mitogen-activated protein kinase kinase kinase 1 | 8906 | -0.177 | -0.3593 | Yes |
| 16 | PLCB3 | PLCB3 StanfordSource, GeneCards | phospholipase C, beta 3 (phosphatidylinositol-specific) | 8985 | -0.184 | -0.3131 | Yes |
| 17 | ELK1 | ELK1 StanfordSource, GeneCards | ELK1, member of ETS oncogene family | 9250 | -0.205 | -0.2790 | Yes |
| 18 | ARAF1 | ARAF1 StanfordSource, GeneCards | v-raf murine sarcoma 3611 viral oncogene homolog 1 | 9608 | -0.250 | -0.2410 | Yes |
| 19 | RRAS | RRAS StanfordSource, GeneCards | related RAS viral (r-ras) oncogene homolog | 9629 | -0.253 | -0.1686 | Yes |
| 20 | NRAS | NRAS StanfordSource, GeneCards | neuroblastoma RAS viral (v-ras) oncogene homolog | 9923 | -0.322 | -0.1031 | Yes |
| 21 | MAP2K1 | MAP2K1 StanfordSource, GeneCards | mitogen-activated protein kinase kinase 1 | 10067 | -0.410 | 0.0032 | Yes |
