GSEA Report for Dataset p53_full_useme_maxed_cs.gct

Enrichment in phenotype: WT (17 samples)

• 143 / 308 gene sets had enrichment in phenotype WT
• 14 gene set(s) are significant at nominal pvalue < 5%
• 5 gene set(s) are significant at FDR < 25%
• Detailed enrichment results in html format
• Detailed enrichment results in excel format (tab delimited text)

Enrichment in phenotype: MUT (33 samples)

• 165 / 308 gene sets had enrichment in phenotype MUT
• 25 gene set(s) are significant at nominal pvalue < 5%
• 2 gene set(s) are significant at FDR < 25%
• Detailed enrichment results in html format
• Detailed enrichment results in excel format (tab delimited text)

Gene markers for the WT versus MUT comparison

• The dataset had 10100 features (genes)
• # of markers for phenotype WT: 5707 (56.5% ) with correlation area 59.8%
• # of markers for phenotype MUT: 4393 (43.5% ) with correlation area 40.2%
• Detailed rank ordered gene list for all features in the dataset
• Heat map and gene list correlation profile for all features in the dataset

Advanced statistics and plots

• Gene set size filters (min=15, max=500) resulted in filtering out 214 / 522 gene sets
• The remaining 308 gene sets were used in the analysis. List of gene sets and their sizes (restricted to probes in the specified dataset)
• Enrichment results and additional statistics for phenotype WT (excel, html)
• Enrichment results and additional statistics for phenotype MUT (excel, html)
• Plot of p-values vs. NES
• Plot of global observed and null densities (after area normalization)
• Global ES histogram

Other

• Parameters used for this analysis