Human Gene Set: GOCC_AMPA_GLUTAMATE_RECEPTOR_COMPLEX

For the Mouse gene set with the same name, see GOCC_AMPA_GLUTAMATE_RECEPTOR_COMPLEX

Standard name GOCC_AMPA_GLUTAMATE_RECEPTOR_COMPLEX
Systematic name M17189
Brief description An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus. [GOC:ef]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:CC: GO Cellular Component
Source publication  
Exact source GO:0032281
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0032281
Filtered by similarity ?
Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 30 genes
Gene families ? Categorize these 30 genes by gene family
Show members (show 30 source identifiers mapped to 30 genes)
Version history 2024.1.Hs: Updated to GO Release 2024-04-24.

See MSigDB license terms here. Please note that certain gene sets have special access terms.