Human Gene Set: GOCC_EUKARYOTIC_TRANSLATION_INITIATION_FACTOR_2B_COMPLEX

For the Mouse gene set with the same name, see GOCC_EUKARYOTIC_TRANSLATION_INITIATION_FACTOR_2B_COMPLEX

Standard name GOCC_EUKARYOTIC_TRANSLATION_INITIATION_FACTOR_2B_COMPLEX
Systematic name M25661
Brief description A multisubunit guanine nucleotide exchange factor which catalyzes the exchange of GDP bound to initiation factor eIF2 for GTP, generating active eIF2-GTP. In humans, it is composed of five subunits, alpha, beta, delta, gamma and epsilon. [PMID:9438375]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:CC: GO Cellular Component
Source publication  
Exact source GO:0005851
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0005851
Filtered by similarity ?
Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 5 genes
Gene families ? Categorize these 5 genes by gene family
Show members (show 5 source identifiers mapped to 5 genes)
Version history 2026.1.Hs: Updated to GO Release 2025-10-10.


Creative Commons Attribution 4.0 International License (CC-BY-4.0)

The contents of this gene set are protected by copyright (c) 2004-2026 Broad Institute, Inc., Massachusetts Institute of Technology, and Regents of the University of California, subject to the terms and conditions of the Creative Commons Attribution 4.0 International License.

See the full MSigDB license terms here.