Human Gene Set: HP_DECREASED_NAIVE_CD8_T_CELL_PROPORTION


Standard name HP_DECREASED_NAIVE_CD8_T_CELL_PROPORTION
Systematic name M50918
Brief description Decreased naive CD8+ T cell proportion
Full description or abstract Abnormal decrease of the naive CD8+ T cell subpopulation, commonly characterized as CD45RA+, CD45RO-, or CD27+, measured as percentage of total CD8+ T cells in the blood, compared to a reference range for a given sex and age-group. These cells are sometimes also characterized as CD62L+ and CCR7+. [PMID:26700072]
Collection C5: Ontology
      HPO: Human Phenotype Ontology
Source publication  
Exact source HP:0410377
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External links https://hpo.jax.org/app/browse/term/HP:0410377
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Source species Homo sapiens
Contributed by Human Phenotype Ontology Group (The Jackson Laboratory (JAX))
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
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Version history 2026.1.Hs: Updated to HPO Release 2026-01-08.


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