Human Gene Set: HP_IMPAIRED_ANTIGEN_SPECIFIC_RESPONSE


Standard name HP_IMPAIRED_ANTIGEN_SPECIFIC_RESPONSE
Systematic name M38470
Brief description Impaired antigen-specific response
Full description or abstract An impaired immune response mediated by cells expressing specific receptors for antigen produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory). []
Collection C5: Ontology
      HPO: Human Phenotype Ontology
Source publication  
Exact source HP:0031404
Related gene sets  
External links https://hpo.jax.org/app/browse/term/HP:0031404
Filtered by similarity ?
Source species Homo sapiens
Contributed by Human Phenotype Ontology Group (The Jackson Laboratory (JAX))
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 60 genes
Gene families ? Categorize these 60 genes by gene family
Show members (show 60 source identifiers mapped to 60 genes)
Version history 2025.1.Hs: Updated to HPO Release 2025-05-06.

See MSigDB license terms here. Please note that certain gene sets have special access terms.