For the Mouse gene set with the same name, see BIOCARTA_BCELLSURVIVAL_PATHWAY

Systematic name M4835
Brief description B Cell Survival Pathway
Full description or abstract Physical interactions between intergrin alpha4beta1 heterodimer expressed on B cells and counter receptors on stroma cells are key mediators of the survival of normal and malignant B cells. Recent data indicate that integrin stimulation increases FBI-1, XIAP, surviving, and CCT4 expression but inhibits Requiem, c-Fos, and caspase 3 and 7 induction.
Collection C2: Curated
      CP: Canonical Pathways
            CP:BIOCARTA: BioCarta Pathways
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Source species Homo sapiens
Contributed by BioCarta
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Version history 7.0: Changed members. Upgraded to final version of Biocarta.

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