Gene Set: BIOCARTA_IL3_PATHWAY

Standard name BIOCARTA_IL3_PATHWAY
Systematic name M17681
Brief description IL 3 signaling pathway
Full description or abstract Interleukin-3 promotes the proliferation and differentiation of hematopoietic cells through binding to its receptor. The receptor for IL-3 is a heterodimer with a ligand-specific alpha chain (70 kD, CD123) and a common beta chain (shared with IL-5 and GM-CSF). Signaling is believed to be primarily through Stat5 and the MAPK pathways.
Collection C2: curated gene sets
      CP: canonical pathways
            CP:BIOCARTA: BioCarta gene sets
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External links https://data.broadinstitute.org/gsea-msigdb/msigdb/biocarta/human/h_il3Pathway.gif
Filtered by similarity
Organism Homo sapiens
Contributed by BioCarta
Source platform HUMAN_SEQ_ACCESSION
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Compendia expression profiles GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
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Version history 7.0: Changed members. Upgraded to final version of Biocarta.

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