Human Gene Set: BRCA1_DN.V1_DN

Standard name BRCA1_DN.V1_DN
Systematic name M2747
Brief description Genes down-regulated in MCF10A cells (breast cancer) upon knockdown of BRCA1 [GeneID=672] gene by RNAi.
Full description or abstract MCF10A cells in 3-D culture for 15 h after treatment with BRCA1-RNAi vs Luc-RNAi adenovirus
Collection C6: Oncogenic Signature
Source publication Pubmed 16843262   Authors: Furuta S,Wang JM,Wei S,Jeng YM,Jiang X,Gu B,Chen PL,Lee EY,Lee WH
Exact source BRCA1 KD vs LUC KD; bottom 150 genes (diff. of means)
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(show 2 gene sets from the same authors)
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Source species Homo sapiens
Contributed by Pablo Tamayo (Broad Institute)
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Compendia expression profiles ? GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
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