Systematic name M2310
Brief description Genes down-regulated by MYC [GeneID=4609], according to the MYC Target Gene Database.
Full description or abstract We report a database of genes responsive to the Myc oncogenic transcription factor. The database Myc Target Gene prioritizes candidate target genes according to experimental evidence and clusters responsive genes into functional groups. We coupled the prioritization of target genes with phylogenetic sequence comparisons to predict c-Myc target binding sites, which are in turn validated by chromatin immunoprecipitation assays. This database is essential for the understanding of the genetic regulatory networks underlying the genesis of cancers.
Collection C2: curated gene sets
      CGP: chemical and genetic perturbations
Source publication Pubmed 14519204   Authors: Zeller KI,Jegga AG,Aronow BJ,O'Donnell KA,Dang CV
Exact source
Related gene sets (show 4 additional gene sets from the source publication)

(show 15 gene sets from the same authors)
External links  
Filtered by similarity
Organism Homo sapiens
Contributed by Chi Dang (Johns Hopkins University)
Source platform Human_NCBI_Gene_ID
Dataset references  
Download gene set format: grp | text | gmt | gmx | xml
Compute overlaps (show collections to investigate for overlap with this gene set)
Compendia expression profiles GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 251 genes
Gene families Categorize these 251 genes by gene family
Show members (show 253 members mapped to 251 genes)
Version history  

See MSigDB license terms here. Please note that certain gene sets have special access terms.