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Human Gene Set: GOBP_CANONICAL_WNT_SIGNALING_PATHWAY
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Standard name | GOBP_CANONICAL_WNT_SIGNALING_PATHWAY_INVOLVED_IN_CARDIAC_MUSCLE_CELL_FATE_COMMITMENT | ||||||||||||||||||||||||
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Systematic name | M40485 | ||||||||||||||||||||||||
Brief description | The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin and contributing to cardiac muscle cell fate commitment. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. [GOC:mtg_heart, PMID:17576928] | ||||||||||||||||||||||||
Full description or abstract | |||||||||||||||||||||||||
Collection | C5: Ontology GO: Gene Ontology GO:BP: GO Biological Process |
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Exact source | GO:0061317 | ||||||||||||||||||||||||
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External links | http://amigo.geneontology.org/amigo/term/GO:0061317 |
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Filtered by similarity ? | |||||||||||||||||||||||||
Source species | Homo sapiens | ||||||||||||||||||||||||
Contributed by | Gene Ontology (Gene Ontology Consortium) | ||||||||||||||||||||||||
Source platform or identifier namespace |
Human_NCBI_Gene_ID | ||||||||||||||||||||||||
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