Human Gene Set: GOBP_CYTOPLASMIC_PATTERN_RECOGNITION
      _RECEPTOR_SIGNALING_PATHWAY_IN_RESPONSE
      _TO_VIRUS

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For the Mouse gene set with the same name, see GOBP_CYTOPLASMIC_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY_IN_RESPONSE_TO_VIRUS

Standard name GOBP_CYTOPLASMIC_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY_IN_RESPONSE_TO_VIRUS
Systematic name M23483
Brief description The series of molecular signals initiated by the binding of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. Cytosolic PRRs such as RIG-I (DDX58) and MDA-5 (IFIH1) detect RNA synthesized during active viral replication and trigger a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines. [GOC:bf, PMID:17328678, PMID:18272355, PMID:19531363]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:BP: GO Biological Process
Source publication  
Exact source GO:0039528
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0039528
Filtered by similarity ?
Organism Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform Human_NCBI_Gene_ID
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 35 genes
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Show members (show 35 members mapped to 35 genes)
Version history 2022.1.Hs: Updated to GO Release 2022-07-01, NCBI gene2go 2022-07-15.

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