Human Gene Set: GOBP_LEUKOCYTE_TETHERING_OR_ROLLING

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For the Mouse gene set with the same name, see GOBP_LEUKOCYTE_TETHERING_OR_ROLLING

Standard name GOBP_LEUKOCYTE_TETHERING_OR_ROLLING
Systematic name M23922
Brief description Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection). [GOC:bf, ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538, Wikipedia:Leukocyte_extravasation]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:BP: GO Biological Process
Source publication  
Exact source GO:0050901
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0050901
Filtered by similarity ?
Organism Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform Human_NCBI_Gene_ID
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 33 genes
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Show members (show 33 members mapped to 33 genes)
Version history 2022.1.Hs: Updated to GO Release 2022-07-01, NCBI gene2go 2022-07-15.

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