Systematic name M452
Brief description Genes down-regulated in control CD4 [GeneID=920] T cell versus those infected with HIV-1 viruses lacking Env and Nef.
Full description or abstract The high mutation rate of HIV is linked to the generation of viruses expressing proteins with altered function whose impact on disease progression is unknown. We investigated the effects of HIV-1 viruses lacking Env, Vpr and Nef on CD4+ T cell gene expression using high-density DNA microarray analysis and functional assays.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 19050264   Authors: Dabrowska A,Kim N,Aldovini A
Exact source GSE12963_2628_200_DN
Related gene sets (show 5 additional gene sets from the source publication)
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Source species Homo sapiens
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
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Compendia expression profiles ? GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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