Human Gene Set: GSE13229_MATURE_VS_INTMATURE_NKCELL_UP

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Standard name GSE13229_MATURE_VS_INTMATURE_NKCELL_UP
Systematic name M3213
Brief description Genes up-regulated in comparison of mature NK cells versus intermediate mature KN cells.
Full description or abstract Previous reports have defined three subsets of mouse NK cells on the basis of the expression of CD27 and CD11b. The developmental relationship between these subsets was unclear. To address this issue, we evaluated the overall proximity between mouse NK cell subsets defined by CD27 and CD11b expression using pangenomic gene expression profiling. The results suggest that CD27+CD11b-, CD27+CD11b+ and CD27-CD11b+ correspond to three different intermediates stages of NK cell development.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 19234143   Authors: Chiossone L,Chaix J,Fuseri N,Roth C,Vivier E,Walzer T
Exact source GSE13229_2031_200_UP
Related gene sets (show 5 additional gene sets from the source publication)

(show 26 gene sets from the same authors)
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Organism Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
Source platform HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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