Human Gene Set: GSE18148_CBFB_KO_VS_WT_TREG_DN

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Standard name GSE18148_CBFB_KO_VS_WT_TREG_DN
Systematic name M4252
Brief description Genes down-regualted in comparison of regulatory T cell (Treg) from CBFB [GeneID=865] deficient mice versus those from wild type animals.
Full description or abstract Gene expression profiles of Cbfb-deficient and control Treg cells were compared. Naturally arising regulatory T (Treg) cells express the transcription factor FoxP3, which critically controls the development and function of Treg cells. FoxP3 interacts with
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 19800266   Authors: Kitoh A,Ono M,Naoe Y,Ohkura N,Yamaguchi T,Yaguchi H,Kitabayashi I,Tsukada T,Nomura T,Miyachi Y,Taniuchi I,Sakaguchi S
Exact source GSE18148_1212_200_DN
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(show 40 gene sets from the same authors)
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Organism Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
Source platform HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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