Human Gene Set: GSE19923_E2A_KO_VS_E2A_AND_HEB_KO_DP_THYMOCYTE_DN


Standard name GSE19923_E2A_KO_VS_E2A_AND_HEB_KO_DP_THYMOCYTE_DN
Systematic name M7276
Brief description Genes down-regulated in double positve thymocyte: TCF3 [GeneID=6929] knockout versus TCF3 and TCF12 [GeneID=6929;6938] knockout.
Full description or abstract We wanted to test the role of mammalian E proteins E2A and HEB in the development of T cells. Using a conditional deletion system in which these proteins are deleted at the DP stage of T cell development, we compared DP thymocytes deficient for E2A, HEB or both to wild-type thymocytes
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 20154672   Authors: D'Cruz LM,Knell J,Fujimoto JK,Goldrath AW
Exact source GSE19923_2928_200_DN
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Source species Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
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identifier namespace		 HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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