Human Gene Set: GSE19923_WT_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN

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Standard name GSE19923_WT_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN
Systematic name M7269
Brief description Genes down-regulated in double positive thymocytes: wildtype versus TCF3 and TCF12 [GeneID=6929;6938] knockout.
Full description or abstract We wanted to test the role of mammalian E proteins E2A and HEB in the development of T cells. Using a conditional deletion system in which these proteins are deleted at the DP stage of T cell development, we compared DP thymocytes deficient for E2A, HEB or both to wild-type thymocytes
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 20154672   Authors: D'Cruz LM,Knell J,Fujimoto JK,Goldrath AW
Exact source GSE19923_2927_200_DN
Related gene sets (show 11 additional gene sets from the source publication)

(show 39 gene sets from the same authors)
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Organism Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
Source platform HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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