Human Gene Set: GSE24142_ADULT_VS_FETAL_DN2_THYMOCYTE_UP

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Standard name GSE24142_ADULT_VS_FETAL_DN2_THYMOCYTE_UP
Systematic name M4579
Brief description Genes up-regulated in comparison of adult DN2 thymocytes versus fetal DN2 thymocytes.
Full description or abstract Development of T-cells provides a unique opportunity to study cell-fate determination due to the accessability and the well defined stages of developmental stages. In order to understand the genetic programs underlying fetal and adult T?cell fate specification we subjected highly purified fetal and adult T-cell progenitor populations to a genome?wide transcriptional analysis. The aim was to identify molecular elements that govern T-cell fate specification as a whole but ultimately to isolate elements that were specific for a given population in a specific developmental window.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 22581009   Authors: Belyaev NN,Biró J,Athanasakis D,Fernandez-Reyes D,Potocnik AJ
Exact source GSE24142_2158_200_UP
Related gene sets (show 23 additional gene sets from the source publication)
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Organism Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
Source platform HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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