Human Gene Set: GSE24142_DN2_VS_DN3_THYMOCYTE_FETAL_DN


Standard name GSE24142_DN2_VS_DN3_THYMOCYTE_FETAL_DN
Systematic name M4575
Brief description Genes down-regulated in comparison of fetal DN2 thymocytes versus fetal DN3 thymocytes.
Full description or abstract Development of T-cells provides a unique opportunity to study cell-fate determination due to the accessability and the well defined stages of developmental stages. In order to understand the genetic programs underlying fetal and adult T?cell fate specification we subjected highly purified fetal and adult T-cell progenitor populations to a genome?wide transcriptional analysis. The aim was to identify molecular elements that govern T-cell fate specification as a whole but ultimately to isolate elements that were specific for a given population in a specific developmental window.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 22581009   Authors: Belyaev NN,Biró J,Athanasakis D,Fernandez-Reyes D,Potocnik AJ
Exact source GSE24142_2156_200_DN
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Source species Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
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HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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