Systematic name M8054
Brief description Genes down-regulated in macrophages: wildtype versus PPARG [GeneID=5468] knockout.
Full description or abstract PPARg is a nuclear receptor that plays an important role in lipid metabolism, homeostasis and immunity. Microarray analysis of gene expression was performed in macrophages from WT and PPARg KO mice. Differentially expressed genes were selected for further analysis.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 21135166   Authors: Roszer T,Menéndez-Gutiérrez MP,Lefterova MI,Alameda D,Núñez V,Lazar MA,Fischer T,Ricote M
Exact source GSE24292_2713_200_DN
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(show 6 gene sets from the same authors)
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Source species Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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