Systematic name M8143
Brief description Genes down-regulated in neutrophils under hypoxia: EGLN3 [GeneID=112399] knockout versus wildtype.
Full description or abstract Neutrophils were isolated form peripheral blood of wildtype and Phd3 null mice, cultured for 4 hours in hypoxia (3% O2) and micro array analysis performed The aim of the present study is to identify the mechanism by which phd3 is required for the hypoxia mediated survival of neutrophils
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 21317538   Authors: Walmsley SR,Chilvers ER,Thompson AA,Vaughan K,Marriott HM,Parker LC,Shaw G,Parmar S,Schneider M,Sabroe I,Dockrell DH,Milo M,Taylor CT,Johnson RS,Pugh CW,Ratcliffe PJ,Maxwell PH,Carmeliet P,Whyte MK
Exact source GSE26023_3381_200_DN
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Source species Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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