Human Gene Set: GSE29615_CTRL_VS_DAY7_LAIV_FLU_VACCINE_PBMC_UP

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Standard name GSE29615_CTRL_VS_DAY7_LAIV_FLU_VACCINE_PBMC_UP
Systematic name M4918
Brief description Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from LAIV influenza vaccine pre-vaccination versus those at day 7 post-vaccination.
Full description or abstract Systems vaccinology has emerged as an interdisciplinary field that combines systems wide measurements and network and predictive modeling applied to vaccinology. Here we used the systems vaccinology approach to study the molecular mechanisms underlying the innate responses to the trivalent inactivated influenza (TIV) and live attenuated influenza (LAIV) vaccination in humans, and to identify early gene signatures that predict the magnitude of the antibody responses to influenza vaccination.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 21743478   Authors: Nakaya HI,Wrammert J,Lee EK,Racioppi L,Marie-Kunze S,Haining WN,Means AR,Kasturi SP,Khan N,Li GM,McCausland M,Kanchan V,Kokko KE,Li S,Elbein R,Mehta AK,Aderem A,Subbarao K,Ahmed R,Pulendran B
Exact source GSE29615_2227_200_UP
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(show 233 gene sets from the same authors)
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Organism Homo sapiens
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
Source platform HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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