Human Gene Set: GSE3400_UNTREATED_VS_IFNB_TREATED_MEF_UP

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Standard name GSE3400_UNTREATED_VS_IFNB_TREATED_MEF_UP
Systematic name M6133
Brief description Genes up-regulated in mouse embryonic fibroblasts (MEF): untreated versus interferon beta.
Full description or abstract A number of IFN-induced proteins are believed to be responsible for the antiviral state induced by IFNs. Our microarray analysis of IFN-regulated genes in MEFs from wild-type mice identified 124 probe sets that were differentially regulated upon IFN treatment. This group consisted of many known ISGs such as Ifit1, Gbp2, mx1, Isg15, Stat1, nmi, mx2, If204, Adar, Irf1, and protein kinase R.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 15131130   Authors: Pfeffer LM,Kim JG,Pfeffer SR,Carrigan DJ,Baker DP,Wei L,Homayouni R
Exact source GSE3400_3548_200_UP
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(show 76 gene sets from the same authors)
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Organism Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
Source platform HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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