Systematic name M5996
Brief description Genes down-regulated in macrophages: untreated versus IL6 [GeneID=3569] for 400min.
Full description or abstract Effects of SOCS3 on the transcriptional response of bone marrow-derived macrophages to IL-6. Fetal liver cells from SOCS3+/+ or SOCS3-/- embryos were used to reconstitute recipient mice. Donor derived bone marrow from these mice was differentiated to macrophages. Macrophages were either unstimulated, or stimulated for 100 or 400 minutes with 10 ng/ml IL-6.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 12754506   Authors: Lang R,Pauleau AL,Parganas E,Takahashi Y,Mages J,Ihle JN,Rutschman R,Murray PJ
Exact source GSE411_2910_200_DN
Related gene sets (show 17 additional gene sets from the source publication)

(show 191 gene sets from the same authors)
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Source species Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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