Human Gene Set: HOXA9_DN.V1_DN

Standard name HOXA9_DN.V1_DN
Systematic name M2848
Brief description Genes down-regulated in MOLM-14 cells (AML) with knockdown of HOXA9 [GeneID=3205] gene by RNAi vs controls.
Full description or abstract RNA was purified from t(9;11) MOLM-14 AML cells 44h after transduction in triplicates with 2 of the two most effective HOXA9shRNA constructs (3 x 1F3-HOXA9shRNA; 3 x 2A5-HOXA9shRNA) or GFP-controlshRNA (6x).
Collection C6: Oncogenic Signature
Source publication Pubmed 19056693   Authors: Faber J,Krivtsov AV,Stubbs MC,Wright R,Davis TN,van den Heuvel-Eibrink M,Zwaan CM,Kung AL,Armstrong SA
Exact source HOXA9sh vs GFPshl; top 200 genes (diff-means)
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(show 6 gene sets from the same authors)
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Source species Homo sapiens
Contributed by Pablo Tamayo (Broad Institute)
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