Human Gene Set: HOXA9_DN.V1_UP

Standard name HOXA9_DN.V1_UP
Systematic name M2850
Brief description Genes up-regulated in MOLM-14 cells (AML) with knockdown of HOXA9 [GeneID=3205] gene by RNAi vs controls.
Full description or abstract RNA was purified from t(9;11) MOLM-14 AML cells 44h after transduction in triplicates with 2 of the two most effective HOXA9shRNA constructs (3 x 1F3-HOXA9shRNA; 3 x 2A5-HOXA9shRNA) or GFP-controlshRNA (6x).
Collection C6: Oncogenic Signature
Source publication Pubmed 19056693   Authors: Faber J,Krivtsov AV,Stubbs MC,Wright R,Davis TN,van den Heuvel-Eibrink M,Zwaan CM,Kung AL,Armstrong SA
Exact source HOXA9sh vs GFPshl; top 200 genes (diff-means)
Related gene sets (show 1 additional gene sets from the source publication)

(show 6 gene sets from the same authors)
External links
Filtered by similarity ?
Source species Homo sapiens
Contributed by Pablo Tamayo (Broad Institute)
Source platform or
identifier namespace
Dataset references (show 1 datasets)
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 192 genes
Gene families ? Categorize these 192 genes by gene family
Show members (show 200 source identifiers mapped to 192 genes)
Version history  

See MSigDB license terms here. Please note that certain gene sets have special access terms.