Human Gene Set: IL21_UP.V1_DN


Standard name IL21_UP.V1_DN
Systematic name M2824
Brief description Genes down-regulated in Sez-4 cells (T lymphocyte) that were first starved of IL2 [GeneID=3558] and then stimulated with IL21 [GeneID=59067].
Full description or abstract Sez-4 cell line was starved of IL2 for 16h, washed twice and placed into 6-well plates in 10ml RPMI (10% FBS) for 2 h followed by addition of IL-21 (100 ng/ml) or medium alone for 4 h.
Collection C6: Oncogenic Signature
Source publication Pubmed 18281483   Authors: Marzec M,Halasa K,Kasprzycka M,Wysocka M,Liu X,Tobias JW,Baldwin D,Zhang Q,Odum N,Rook AH,Wasik MA
Exact source Sez-4 cells starved of IL-2 and activated with IL-21 vs Sez-4 cells starved of IL-2; bottom 200 genes (diff. of means)
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Source species Homo sapiens
Contributed by Pablo Tamayo (Broad Institute)
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identifier namespace		 HUMAN_GENE_SYMBOL
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