Standard name JAK_STAT_CASCADE
Systematic name M11564
Brief description Genes annotated by the GO term GO:0007259. The processes by which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of cytokines to their cognate receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.
Full description or abstract  
Collection ARCHIVED: Archived Founder gene sets that are referenced by current Hallmarks
      C5_GO:BP: Archived GO biological process
Source publication  
Exact source GO:0007259
Related gene sets  
External links
Filtered by similarity
Organism Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform HUMAN_GENE_SYMBOL
Dataset references  
Download gene set format: grp | text | gmt | gmx | xml
Compute overlaps
Compendia expression profiles
Advanced query
Gene families
Show members (show 31 members mapped to 31 genes)
Version history 5.2: Archived


See MSigDB license terms here. Please note that certain gene sets have special access terms.