Gene Set: JNK_DN.V1_DN

Standard name JNK_DN.V1_DN
Systematic name M2745
Brief description Genes down-regulated in JNK inhibitor-treated (SP600125[PubChem=8515]) keratinocytes.
Full description or abstract Keratinocytes are grown to ~75% confluence and either treated with 5nM SP600125, or left untreated. Samples are harvested 1, 4, 24 and 48 h post-treatment.
Collection C6: oncogenic signature gene sets
Source publication Pubmed 16648634   Authors: Gazel A,Banno T,Walsh R,Blumenberg M
Exact source SP600125 experiment CONTROL vs TREATED; top 200 genes (diff. of means)
Related gene sets (show 1 additional gene sets from the source publication)
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Organism Homo sapiens
Contributed by Pablo Tamayo (Broad Institute)
Source platform HUMAN_GENE_SYMBOL
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Compendia expression profiles GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
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