Human Gene Set: JNK_DN.V1_UP


Standard name JNK_DN.V1_UP
Systematic name M2746
Brief description Genes up-regulated in JNK inhibitor-treated (SP600125[PubChem=8515]) keratinocytes.
Full description or abstract Keratinocytes are grown to ~75% confluence and either treated with 5nM SP600125, or left untreated. Samples are harvested 1, 4, 24 and 48 h post-treatment.
Collection C6: Oncogenic Signature
Source publication Pubmed 16648634   Authors: Gazel A,Banno T,Walsh R,Blumenberg M
Exact source SP600125 experiment CONTROL vs TREATED; bottom 200 genes (diff. of means)
Related gene sets (show 1 additional gene sets from the source publication)
External links
Filtered by similarity ?
Source species Homo sapiens
Contributed by Pablo Tamayo (Broad Institute)
Source platform or
identifier namespace		 HUMAN_GENE_SYMBOL
Dataset references (show 1 datasets)
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 186 genes
Gene families ? Categorize these 186 genes by gene family
Show members (show 200 source identifiers mapped to 186 genes)
Version history  

See MSigDB license terms here. Please note that certain gene sets have special access terms.