Gene Set: KEGG_CYSTEINE_AND_METHIONINE_METABOLISM

Standard name KEGG_CYSTEINE_AND_METHIONINE_METABOLISM
Systematic name M10911
Brief description Cysteine and methionine metabolism
Full description or abstract Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, methionine is synthesized from aspartate. S-Adenosylmethionine (SAM), synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway.
Collection C2: curated gene sets
      CP: canonical pathways
            CP:KEGG: KEGG gene sets
Source publication  
Exact source hsa00270
Related gene sets  
External links http://www.genome.jp/kegg/pathway/hsa/hsa00270.html
Filtered by similarity
Organism Homo sapiens
Contributed by KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform Human_NCBI_Gene_ID
Dataset references  
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Compendia expression profiles GTEx compendium
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