Gene Set: KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY

Standard name KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY
Systematic name M15913
Brief description RIG-I-like receptor signaling pathway
Full description or abstract Specific families of pattern recognition receptors are responsible for detecting viral pathogens and generating innate immune responses. Non-self RNA appearing in a cell as a result of intracellular viral replication is recognized by a family of cytosolic RNA helicases termed RIG-I-like receptors (RLRs). The RLR proteins include RIG-I, MDA5, and LGP2 and are expressed in both immune and nonimmune cells. Upon recognition of viral nucleic acids, RLRs recruit specific intracellular adaptor proteins to initiate signaling pathways that lead to the synthesis of type I interferon and other inflammatory cytokines, which are important for eliminating viruses.
Collection C2: curated gene sets
      CP: canonical pathways
            CP:KEGG: KEGG gene sets
Source publication  
Exact source hsa04622
Related gene sets  
External links http://www.genome.jp/kegg/pathway/hsa/hsa04622.html
Filtered by similarity
Organism Homo sapiens
Contributed by KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform Human_NCBI_Gene_ID
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