Human Gene Set: MIZUSHIMA_AUTOPHAGOSOME_FORMATION
For the Mouse gene set with the same name, see MIZUSHIMA_AUTOPHAGOSOME_FORMATION
Standard name
MIZUSHIMA_AUTOPHAGOSOME_FORMATION
Systematic name
M2537
Brief description
Key proteins in mammalian autophagosome formation.
Full description or abstract
Autophagy has been implicated in many physiological and pathological processes. Accordingly, there is a growing scientific need to accurately identify, quantify, and manipulate the process of autophagy. However, as autophagy involves dynamic and complicated processes, it is often analyzed incorrectly. In this Primer, we discuss methods to monitor autophagy and to modulate autophagic activity, with a primary focus on mammalian macroautophagy.
Collection
C2: Curated CGP: Chemical and Genetic Perturbations
Source publication
Pubmed 20144757 Authors: Mizushima N,Yoshimori T,Levine B
Exact source
Table 1
Related gene sets
(show 4 gene sets from the same authors)
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Source species
Mus musculus
Contributed by
Arthur Liberzon (MSigDB Team)
Source platform or identifier namespace
MOUSE_GENE_SYMBOL
Dataset references
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these 12 genes
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12 genes by gene family
Show members
(show 30 source identifiers mapped to 12 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
Ambra1
55626
AMBRA1
autophagy and beclin 1 regulator 1 [Sourc...
Atg10
83734
ATG10
autophagy related 10 [Source:HGNC Symbol;...
Atg101
60673
ATG101
autophagy related 101 [Source:HGNC Symbol...
Atg12
9140
ATG12
autophagy related 12 [Source:HGNC Symbol;...
Atg13
9776
ATG13
autophagy related 13 [Source:HGNC Symbol;...
Atg14
22863
ATG14
autophagy related 14 [Source:HGNC Symbol;...
Atg16L1
Atg2
Atg3
64422
ATG3
autophagy related 3 [Source:HGNC Symbol;A...
Atg4A
Atg4B
Atg4C
Atg4D
Atg5
9474
ATG5
autophagy related 5 [Source:HGNC Symbol;A...
Atg7
10533
ATG7
autophagy related 7 [Source:HGNC Symbol;A...
Atg9
Beclin1
DFCP1
FIP200
GABARAP
GATE-16
11345
GABARAPL2
GABA type A receptor associated protein l...
ULK1
ULK2
VMP1
Vps34
5289
PIK3C3
phosphatidylinositol 3-kinase catalytic s...
WIP1
WIP2
WIP3
WIP4
p150
1639
DCTN1
dynactin subunit 1 [Source:HGNC Symbol;Ac...
Version history
3.1: First introduced
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