Human Gene Set: P53_DN.V2_UP

Standard name P53_DN.V2_UP
Systematic name M2694
Brief description Genes up-regulated in HEK293 cells (kidney fibroblasts) upon knockdown of TP53 [GeneID=7157] gene by RNAi.
Full description or abstract Expression profiling of cells knocked-down for p53 and control un-infected cells and cells infected with siRNA against LacZ.
Collection C6: Oncogenic Signature
Source publication Pubmed 15892871   Authors: Elkon R,Rashi-Elkeles S,Lerenthal Y,Linhart C,Tenne T,Amariglio N,Rechavi G,Shamir R,Shiloh Y
Exact source p53_siRNA vs controls; top 150 genes (diff. of means)
Related gene sets (show 5 additional gene sets from the source publication)

(show 79 gene sets from the same authors)
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Source species Homo sapiens
Contributed by Pablo Tamayo (Broad Institute)
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Compendia expression profiles ? GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
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