Human Gene Set: PTEN_DN.V2_UP

Standard name PTEN_DN.V2_UP
Systematic name M2759
Brief description Genes up-regulated in HCT116 cells (colon carcinoma) upon knockdown of PTEN [GeneID=5728] by RNAi.
Full description or abstract Two HCT116 PTEN+/+ cell lines (parental cells and a clone with random integration of the targeting vector) and three independently-derived HCT116 PTEN-/- cell lines were studied
Collection C6: Oncogenic Signature
Source publication Pubmed 17060456   Authors: Kim JS,Lee C,Bonifant CL,Ressom H,Waldman T
Exact source PTEN ko vs control; top 300 genes (diff. of means)
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Source species Homo sapiens
Contributed by Pablo Tamayo (Broad Institute)
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