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Human Gene Set: REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING
Standard name
REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING
Systematic name
M967
Brief description
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
Full description or abstract
Collection
C2: Curated
CP: Canonical Pathways
CP:REACTOME: Reactome Pathways
Source publication
Exact source
R-HSA-975110
Related gene sets
External links
https://www.reactome.org/content/detail/R-HSA-975110
Filtered by similarity
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Source species
Homo sapiens
Contributed by
Reactome
Source platform or
identifier namespace
Human_Ensembl_Gene_ID
Dataset references
Download gene set
format:
grp
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gmt
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xml
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json
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 13 genes
Gene families
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these 13 genes by gene family
Show members
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show
14 source identifiers mapped to 13 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
ENSG00000143947
6233
RPS27A
ribosomal protein S27a [Source:HGNC ...
ENSG00000150991
7316
UBC
ubiquitin C [Source:HGNC Symbol;Acc:...
ENSG00000170315
7314
UBB
ubiquitin B [Source:HGNC Symbol;Acc:...
ENSG00000172936
4615
MYD88
MYD88 innate immune signal transduct...
ENSG00000175104
7189
TRAF6
TNF receptor associated factor 6 [So...
ENSG00000177889
7334
UBE2N
ubiquitin conjugating enzyme E2 N [S...
ENSG00000184216
3654
IRAK1
interleukin 1 receptor associated ki...
ENSG00000185507
3665
IRF7
interferon regulatory factor 7 [Sour...
ENSG00000196664
51284
TLR7
toll like receptor 7 [Source:HGNC Sy...
ENSG00000198001
51135
IRAK4
interleukin 1 receptor associated ki...
ENSG00000221983
7311
UBA52
ubiquitin A-52 residue ribosomal pro...
ENSG00000239732
54106
TLR9
toll like receptor 9 [Source:HGNC Sy...
ENSG00000244687
7335
UBE2V1
ubiquitin conjugating enzyme E2 V1 [...
ENSG00000276561
3665
IRF7
interferon regulatory factor 7 [Sour...
Version history
2024.1.Hs: Updated to Reactome v89
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