Human Gene Set: SU_LIVER


Standard name SU_LIVER
Systematic name M7054
Brief description Genes up-regulated specifically in human liver tissue.
Full description or abstract High-throughput gene expression profiling has become an important tool for investigating transcriptional activity in a variety of biological samples. To date, the vast majority of these experiments have focused on specific biological processes and perturbations. Here, we have generated and analyzed gene expression from a set of samples spanning a broad range of biological conditions. Specifically, we profiled gene expression from 91 human and mouse samples across a diverse array of tissues, organs, and cell lines. Because these samples predominantly come from the normal physiological state in the human and mouse, this dataset represents a preliminary, but substantial, description of the normal mammalian transcriptome. We have used this dataset to illustrate methods of mining these data, and to reveal insights into molecular and physiological gene function, mechanisms of transcriptional regulation, disease etiology, and comparative genomics. Finally, to allow the scientific community to use this resource, we have built a free and publicly accessible website (http://expression.gnf.org) that integrates data visualization and curation of current gene annotations.
Collection C2: Curated
      CGP: Chemical and Genetic Perturbations
Source publication Pubmed 11904358   Authors: Su AI,Cooke MP,Ching KA,Hakak Y,Walker JR,Wiltshire T,Orth AP,Vega RG,Sapinoso LM,Moqrich A,Patapoutian A,Hampton GM,Schultz PG,Hogenesch JB
Exact source Table 1S: Max Tissue=Liver
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Source species Homo sapiens
Contributed by John Newman (University of Washington)
Source platform or
identifier namespace		 AFFY_HG_U95
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Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
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Version history 3.0: Renamed from HUMAN_TISSUE_LIVER

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