Human Gene Set: YAP1_UP


Standard name YAP1_UP
Systematic name M2845
Brief description Genes up-regulated in MCF10A cells (breast cancer) over-expressing YAP1 [GeneID=10413] gene.
Full description or abstract MCF10A cells were infected with retrovirus constructs (vector or YAP) and puromycin was used to select for transduced cells. Cells were split and grown to ~60-75%% confluency at which point they were harvested for RNA. Vector vs. YAP comparison was done in duplicate.
Collection C6: Oncogenic Signature
Source publication Pubmed 18413746   Authors: Zhang J,Smolen GA,Haber DA
Exact source YAP1 vs control; top 50 genes
Related gene sets (show 1 additional gene sets from the source publication)

(show 96 gene sets from any of these authors)
External links
Filtered by similarity ?
Source species Homo sapiens
Contributed by Pablo Tamayo (Broad Institute)
Source platform or
identifier namespace		 HUMAN_GENE_SYMBOL
Dataset references (show 1 datasets)
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 47 genes
Gene families ? Categorize these 47 genes by gene family
Show members (show 50 source identifiers mapped to 47 genes)
Version history  

See MSigDB license terms here. Please note that certain gene sets have special access terms.