Gene Set: FAN_OVARY_CL17_PUTATIVE_APOPTOTIC_SMOOTH_MUSCLE_CELL

Standard name FAN_OVARY_CL17_PUTATIVE_APOPTOTIC_SMOOTH_MUSCLE_CELL
Systematic name M41719
Brief description The clusters of smooth muscle cells (CL14, CL17) also showed features of growth and remodeling: many DEGs of CL17 (such as CRYAB, GJA4) were involved in regulation of immune response and apoptosis, whereas DEGs of CL14 (such as ACTA2, PLN, ADIRF, and MYH11) associated with mature smooth muscle cells (Fig. 3e-g).
Full description or abstract  
Collection C8: cell type signature gene sets
Source publication Pubmed 31320652   Authors: Fan X,Bialecka M,Moustakas I,Lam E,Torrens-Juaneda V,Borggreven NV,Trouw L,Louwe LA,Pilgram GSK,Mei H,van der Westerlaken L,Chuva de Sousa Lopes SM
Exact source Supplementary Data 2 (complete underlying data received from authors), avg_logFC > 0.25, p_val_adj <0.05
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External links https://doi.org/10.1038/s41467-019-11036-9
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Organism Homo sapiens
Contributed by Anthony Castanza (MSigDB Team)
Source platform HUMAN_GENE_SYMBOL
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NCI-60 cell lines (National Cancer Institute)
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Version history 7.3: First Introduced.

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